Quaternary ammonium salts
Medchemexpress LLC (±)-Carnitine chloride | 461-05-2 | 98.0% | 1 ML
(±)-Carnitine chloride, also known as DL-Carnitine chloride, is a compound with both D and L isomers. L-carnitine plays a vital role in the β-oxidation of fatty acids and exhibits significant antioxidant and anti-inflammatory activities, making it valuable for various biological studies.
- Facilitates shuttling of long-chain fatty acids across the inner mitochondrial membrane.
- Increases palmitoyl-CoA-induced mitochondrial respiration.
- Augments Nrf2 nuclear translocation and HO-1 expression.
- Protects cells against H2O2-induced cell damage via Akt-mediated Nrf2 signaling.
- Down-regulates ubiquitin proteasome pathway and increases IGF-1.
- Alleviates skeletal muscle atrophy in animal models.
- Suppresses atrogin-1 mRNA expression.
- Reduces renal fibrosis and pro-oxidative and proinflammatory states.
- Increases PPAR-γ expression.
Medchemexpress LLC Hexanoyl-coenzyme A triammonium | 799812-81-0 | 916.77 | 1 MG
Hexanoyl-coenzyme A triammonium (06:0 Coenzyme A) is a medium-chain fatty acyl CoA. It serves as an acyl donor substrate for ghrelin O-acyltransferase (GOAT).
- Medium-chain fatty acyl CoA
- Acyl donor substrate for ghrelin O-acyltransferase (GOAT)
![eMolecules 6645-46-1 | L-Carnitine hydrochloride | Combi-Blocks | MFCD00066100 | 197.660 | C7H16ClNO3 | 98.000 | [Cl-].C[N+](C)(C)C[C@H](O)CC(O)=O | 5g | 205397247](https://assets.fishersci.com/TFS-Assets/CCG/product-images/NC1600933.jpg-250.jpg)
eMolecules 6645-46-1 | L-Carnitine hydrochloride | Combi-Blocks | MFCD00066100 | 197.660 | C7H16ClNO3 | 98.000 | [Cl-].C[N+](C)(C)C[C@H](O)CC(O)=O | 5g | 205397247
L-Carnitine hydrochloride | Combi-Blocks | 6645-46-1 | MFCD00066100 | 197.660 | C7H16ClNO3 | 98.000 | [Cl-].C[N+](C)(C)C[C@H](O)CC(O)=O | 5g | 205397247
Medchemexpress LLC Acetyl-L-carnitine | 3040-38-8 | 99.7% | 203.24 | 25 MG
Acetyl-L-carnitine | 3040-38-8 | 99.7% | 203.24 | 25 MG
Medchemexpress LLC D-Carnitine | 541-14-0 | 99.9% | 161.20 | 250 MG
D-Carnitine is an orally available isomer of the essential nutrient L-carnitine that promotes long-chain fatty acid transport into the mitochondrial matrix for beta-oxidation. It also exhibits antiparasitic activity.
- Orally available isomer of L-carnitine.
- Promotes long-chain fatty acid transport into the mitochondrial matrix for beta-oxidation.
- Has antiparasitic activity.
- Inhibits the uptake of L-carnitine by renal brush marginal membrane vesicles in rats (at 0.5 μM).
- Inhibits the uptake of L-carnitine by primary human limbal (HCLE) and conjunctival epithelium (HCjE) cells (at 0.5, 1 μM).
- Inhibits parasite activity in rats and mice infected with trypanosoma (at 75-300 mg/kg/day, orally).
Lkt Laboratories CAS 6645-46-1, ≥98%, Endogenous quaternary ammonium required for fatty acid transport. Increases muscle carnitine content and work output while decreasing glycogen utilization during exercise.
L-Carnitine is an endogenous quaternary ammonium compound required for fatty acid transport; it is often given as a dietary supplement. The L-isomer is active, exhibiting anti-osteoporotic, antioxidative, and cardioprotective activities. In a clinical setting, L-carnitine administration increases muscle carnitine content and work output while decreasing glycogen utilization during exercise. Additionally, L-carnitine improves postprandial flow-mediated dilation, slightly increasing vascular function. In animal models, L-carnitine increases bone mineral density and decreases bone resorption. L-Carnitine also improves plasma markers of exercise stress such as malondialdehyde. L-Carnitine improves symptoms of cardiovascular disease accompanying myocardial infarction and decreases ventricular arrhythmias, symptoms of angina, and mortality rates.
Medchemexpress LLC Acetyl-L-carnitine | 3040-38-8 | 99.86% | 203.24 | 50 MG
Acetyl-L-carnitine | 3040-38-8 | 99.86% | 203.24 | 50 MG
Medchemexpress LLC Valeryl-L-carnitine-d3 chloride | 162040-64-4 | 99.9% | 284.79 | 500 UG
Valeryl-L-carnitine-d3 (chloride) is the deuterium labeled Valeryl-L-carnitine chloride. It is for research use only and can be used as a tracer or an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS. Deuteration may affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Cambridge Isotope Laboratories L-Carnitine HCl O-dodecanoyl (unlabeled) 0 1 mg
L-Carnitine HCl O-dodecanoyl (unlabeled) 0 1 mg
Medchemexpress LLC Decanoyl-L-carnitine-d3 (chloride) | 2483831-87-2 | MFCD08705111 | 99.9% | 354.93 | C17H31D3ClNO4 | 5 MG
Decanoyl-L-carnitine-d3 (chloride) is the deuterium-labeled chloride salt of decanoyl-L-carnitine, supplied as an isotopically labeled reagent for use as an internal standard in quantitative mass spectrometry. It is intended for research use and is characterized by high isotopic enrichment and analytical-grade purity suitable for LC-MS and GC-MS workflows.
- Deuterium-labeled internal standard for accurate quantification by LC-MS and GC-MS.
- High chemical purity (>99.9%) for reliable analytical performance.
- Provided as a stable solid, suitable for long-term storage.
- Chloride salt form compatible with common analytical protocols.
- Three deuterium atoms provide a clear mass shift from the native analyte.
Selleck Chemical LLC Acetyl-L-carnitine
O-Acetyl-L-carnitine (Acetyl-L-carnitine O-acetyl-L-carnitine O-Acetylcarnitine) can be synthesis or is naturally found in healthy humans It could help transport fatty acids into the mitochondrial matrix where fatty acid metabolism occurs
Cambridge Isotope Laboratories L-CARNITINE:HCL, O-BUTYRYL (N-METHYL-D3, 98%) 97% CHEMICAL PURITY, 0.01 G, 1334532-21-6
L-CARNITINE:HCL, O-BUTYRYL (N-METHYL-D3, 98%) 97% CHEMICAL PURITY, 0.01 G, 1334532-21-6
Cambridge Isotope Laboratories Carnitine/Acylcarnitine Standard Mix Supplement to NSK-B (unlabeled) 1 vial
Carnitine/Acylcarnitine Standard Mix Supplement to NSK-B (unlabeled) 1 vial
Apexbio Technology LLC L-Carnitine inner salt 541-15-1 10mM (in 1mL DMSO)
L-Carnitine inner salt (CAS 541-15-1) is a naturally occurring quaternary ammonium compound prevalent in mammalian tissues particularly in skeletal and cardiac muscle It facilitates the transport of long-chain fatty acids into mitochondria for -oxidation thereby playing a critical role in cellular energy metabolism By modulating substrate utilization L-carnitine influences the balance between glucose and lipid metabolism It is widely employed in metabolic research to study energy regulation mitochondrial function and disorders involving altered fatty acid oxidation
Medchemexpress LLC L-Carnitine | 541-15-1 | 100.0% | 25 G
L-Carnitine ((R)-Carnitine) is a highly polar, small zwitterion that serves as an essential co-factor for the mitochondrial β-oxidation pathway. It functions by transporting long-chain fatty acyl-CoAs into the mitochondria for degradation. Additionally, L-Carnitine acts as an antioxidant and can ameliorate metabolic imbalances in various inborn errors of metabolism.
- Essential co-factor for mitochondrial β-oxidation pathway.
- Transports long-chain fatty acyl-CoAs into mitochondria.
- Functions as an antioxidant.
- Can ameliorate metabolic imbalances in many inborn errors of metabolism.
- Highly polar, small zwitterion.